ymnas.cn-亚洲天堂av手机在线播放,亚洲国产成人精品女人久久久,欧美一级内射片在线网站观看,精品在线播放亚洲av

<strong id="ji0le"><dl id="ji0le"></dl></strong>

PRODUCT CLASSIFICATION

產品分類

PDE Assay Kits

查看全部產品 >>

TECHNICAL ARTICLES

相關文章

產品展示/ Product display

您的位置：首頁 / 產品展示 / / PDE Assay Kits / 60709PDE10A1 TR-FRET Assay Kit

PDE10A1 TR-FRET Assay Kit

●Purchase●DescriptionPhosphodiesterases(PDEs)playanimportantroleindynamicregulationofcAMPandcGMPsignaling

產品型號：60709
廠商性質：生產廠家
更新時間：2023-11-11
訪問量：379

立即咨詢

聯系電話：

詳細介紹

●

Purchase

●

Description

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE10A is a dual substrate PDE highly expressed in striatal medium spiny neurons. PDE10A inhibitors can improve the cognitive symptoms of schizophrenia, and exhibit potential therapeutic value for Huntington’s disease. PDE10A1 is located in cytosol, whereas PDE10A2 is a membrane-associated protein.

The PDE10A1 TR-FRET Assay Kit is designed for identification of inhibitors of PDE10A1 using TR-FRET (Time Resolved Fluorescence Resonance Energy Transfer) technology. The assay is based on the generation of FAM-labeled nucleotide monophosphates by the phosphodiesterase. These phosphate groups bind to terbium-labeled nanoparticles, resulting in energy transfer from the terbium to the FAM, which emits a fluorescent signal at 520 nm. The change in fluorescent intensity can be easily measured using a fluorescence plate reader.

Using this kit, only two simple steps on a microtiter plate are required for the PDE10A1 activity assay. First, the fluorescent-labeled cAMP is incubated with a sample containing PDE10A1 for 1 hour. Second, a binding agent and a terbium donor are added to the reaction mix and incubated for 1 hour. Then, fluorescence intensity can be measured using a fluorescence reader.

●

Synonyms

inhibitor screening, FRET assay kit, PDE10A1, HTRF

留言詢價

上一篇：60385PDE10A1 Assay Kit
下一篇：60400PDE10A Assay Kit

關注公眾號

郵箱：infocn@bpsbioscience.com

傳真：

地址：上海靜安區

sitmap.xml 管理登陸

TEL：

掃碼加微信

ymnas.cn-亚洲天堂av手机在线播放,亚洲国产成人精品女人久久久,欧美一级内射片在线网站观看,精品在线播放亚洲av

PDE10A1 TR-FRET Assay Kit

留言框

產品：

您的單位：

您的姓名：

聯系電話：

常用郵箱：

省份：

詳細地址：

補充說明：

驗證碼：

ymnas.cn-亚洲天堂av手机在线播放,亚洲国产成人精品女人 久久久,欧美一级内射片在线网站观看,精品在线播放亚洲av

PDE10A1 TR-FRET Assay Kit

留言框

產品：

您的單位：

您的姓名：

聯系電話：

常用郵箱：

省份：

詳細地址：

補充說明：

驗證碼：

ymnas.cn-亚洲天堂av手机在线播放,亚洲国产成人精品女人久久久,欧美一级内射片在线网站观看,精品在线播放亚洲av